The effect of Rheumatoid Arthritis is damage to joints. It happens because the material surrounding the joints becomes inflamed which is common to both hands and legs. The swelling is most common in the wrist and fingers and can also be possible on the neck, shoulders, elbows, hips, knees, ankles and feetThe worst thing other than the condition is that it has along term effect and that is, increasing your difficulty to carry out simple task or household chores. It will also be difficult for you to move from one place to another.