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Press Review (January 12, 2013) – Revue de presse (12 janvier 2013)

Pap Test Could Help Find Cancers of Uterus and Ovaries
The Pap test, which has prevented countless deaths from cervical
cancer, may eventually help to detect cancers of the uterus and
ovaries as well, a new study suggests
By Denise Grady. In New York Times

Sickle Cells Show Potential to Attack Aggressive Cancer Tumors
By harnessing the very qualities that make sickle cell disease a
lethal blood disorder, a research team led by Duke Medicine and
Jenomic, a private cancer research company in Carmel, Calif., has
developed a way to deploy the misshapen red blood cells to fight
cancer tumors.
In Science Daily (press release)

High Fiber Diet Prevents Prostate Cancer Progression, Study Shows
A high-fiber diet may have the clinical potential to control the
progression of prostate cancer in patients diagnosed in early stages
of the disease.
In Science Daily (press release)

Scientists Use Pap Test Fluid to Detect Ovarian, Endometrial Cancers
Using cervical fluid obtained during routine Pap tests, scientists at
the Johns Hopkins Kimmel Cancer Center have developed a test to detect
ovarian and endometrial cancers. In a pilot study, the "PapGene" test,
which relies on genomic sequencing of cancer-specific mutations,
accurately detected all 24 (100 percent) endometrial cancers and nine
of 22 (41 percent) ovarian cancers.
In Science Daily (press release)

Two-Drug Combination May Slow Deadly Thyroid Cancer
A combination of the drugs pazopanib and paclitaxel shows promise in
slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-
led study published in the journal Science Translational Medicine. The
two drugs together resulted in greater anti-cancer activity in ATC
than either drug alone, says lead researcher Keith Bible, M.D., Ph.D.,
a Mayo Clinic oncologist.
In Science Daily (press release)

Ovarian cancer stem cell study puts targeted therapies within reach
Researchers at Yale School of Medicine have identified a key link
between stem cell factors that fuel ovarian cancer's growth and
patient prognosis. The study, which paves the way for developing novel
targeted ovarian cancer therapies, is published online in the current
issue of Cell Cycle. Lead author Yingqun Huang, M.D., associate
professor in the Department of Obstetrics, Gynecology & Reproductive
Sciences, and her colleagues have demonstrated a connection between
two concepts that are revolutionizing the way cancer is treated.
In Eureka! Science News

Microscopic Blood in Urine Unreliable Indicator of Urinary Tract
Microscopic amounts of blood in urine have been considered a risk
factor for urinary tract malignant tumors. However, only a small
proportion of patients referred for investigation are subsequently
found to have cancer. A new Kaiser Permanente Southern California
study published in the February Mayo Clinic Proceedings reports on the
development and testing of a Hematuria Risk Index to predict cancer
risk. This could potentially lead to significant reductions in the
number of unnecessary evaluations.
In Science Daily (press release)

Brief Life Expectancy Should Rule Out Certain Cancer Screenings: Study
Risks outweigh benefits for those with few years left, researchers
In U.S. News & World Report

Oil Sands Raise Levels of Cancer-Causing Compounds in Regional Waters
From carcinogens to acid rain, tar sands development is raising levels
of industrial pollution across the north.
By David Biello. In Scientific American

ASCO Blueprint to Improve Cancer Survivor Care
The American Society of Clinical Oncology (ASCO) has issued
recommendations to keep cancer survivors from falling "through the
cracks." Those words, from ASCO president Sandra Swain, MD, refer to
the health risks that imperil survivors as they transition out of
treatment and the related need for planned and coordinated ongoing
care to catch and mitigate those risks.
By Nick Mulcahy. In Medscape

US Cancer Death Rates Continue to Fall: Report
Deaths from cancer continue to drop for American men and women from
most racial and ethnic groups, according to a new report, with
significant declines seen for lung, colorectal, breast, prostate and
other forms of cancer.
By Steven Reinberg. In


Cancer du sein : la mastectomie chimique а l'essai
Susan Love et coll., qui publient dans « Cancer Prevention Research »
les rйsultats de leurs travaux de phase I, parlent de « mastectomie
chimique ». Il s’agit ni plus ni moins de l’administration d’une
chimiothйrapie par le mamelon.
Par Emmanuel de Viel. Dans Le Quotidien du Mйdecin

La protйine de la maladie de Huntington impliquйe dans le cancer du
On l’ignorait jusque-lа, la protйine huntingtine mutйe, qui est connue
pour кtre responsable de la maladie de Huntigton, est exprimйe dans le
tissu mammaire sain ainsi que dans les tumeurs mammaires.
Par Bйatrice Vuaille. Dans Le Quotidien du Mйdecin

Les bкtabloquants, nouvelle piste contre le cancer du poumon NPC ?
Les patients atteints de cancer bronchique non а petites cellules
(CBNPC) qui reзoivent des bкtabloquants pour une hypertension ou une
cardiopathie en plus d'une radiothйrapie voient leur survie globale
prolongйe de faзon significative par rapport а ceux qui n'en reзoivent
pas, selon une йtude rйtrospective sur 722 patients publiйe dans les
Annals of Oncology.
Par Zosia Chustecka, Aude Lecrubier. Sur Medscape France

USA: recul de la mortalitй due au cancer
Le recul de la mortalitй due au cancer aux Etats-Unis, amorcй au dйbut
des annйes 1990, se poursuit avec une baisse de 1,8% par an de 2000 а
2009 chez les hommes et de 1,4% chez les femmes, selon le dernier
rapport annuel fйdйral publiй aujourd’hui. Chez les enfants jusqu'а
l'вge de 14 ans, le taux de dйcиs dы au cancer a chutй de 1,8% par an.
Dans Le Figaro
Document de base (en anglais) :

CANCER, VIH: Booster le systиme immunitaire via des cellules souches
Ces 2 recherches japonaises, publiйes dans l’йdition du 2 janvier de
la revue Cell Stem Cell dйcrivent l’utilisation de cellules souches
pour cloner et fabriquer de grandes quantitйs de globules blancs qui,
produits par le systиme immunitaire sont capables de reconnaоtre des
marqueurs spйcifiques de cellules tumorales ou de VIH et d’attaquer
ensuite puis tuer les cellules tumorales ou infectйes.
Dans Santй Log

Cancer Blog – Marc Lacroix – Le Blogue du Cancer

Marc Lacroix-Corman – InTextoResearch – Baelen (01/2013)