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People with Type 2 Diabetes More Likely To Get Severe OA

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  1. #1
    Donna G Guest

    Default People with Type 2 Diabetes More Likely To Get Severe OA



    People With Type 2 Diabetes More Likely to Get Severe OA
    New research adds to notion that osteoarthritis is not just a "wear and
    tear" disease.
    By Jim Morelli

    11/6/12 Age and body mass index – the relationship of weight to height
    – are two well-recognized risk factors for the development of
    osteoarthritis, or OA. Now, a new study out of Europe adds type 2
    diabetes to the list. The study, published recently online in Diabetes
    Care, finds that type 2 diabetes doubles the risk of developing
    osteoarthritis that is severe enough to require joint replacement.

    "Data from this study show that age, body mass index and diabetes
    constitute three independent and strong risk factors for joint failure,"
    says study co-author Georg Schett, MD, chief of rheumatology and
    director of the department of internal medicine at the University of
    Erlangen-Nuremberg in Germany.*

    Dr. Schett says one of the strengths of the study is that it was based
    on comprehensive and lengthy patient follow-up. The researchers analyzed
    the medical records of more than 900 diabetic and nondiabetic people
    over 20 years.

    The sample came from the Italian town of Bruneck, in which there is one
    single hospital and very little relocation of residents out of the area.

    The study participants, recruited in 1990 and followed until 2010, were
    examined every five years. The number of diabetic patients in the study
    was comparatively small: 69 patients in all. The nondiabetic patients
    numbered 858.

    The outcome the study focused on was joint replacement surgery. During
    the 20-year period, the researchers found 13 people in the diabetic
    group and 73 people in the nondiabetic group needed either a knee or hip
    replaced because of severe OA. The so-called "intervention rate" – the
    number of people who required total joint replacement, or arthroplasty

    – for the nondiabetic group was 5.3 percent. But for the diabetic
    group, it was 17.7 percent – more than three times greater. When age,
    body mass index and several other factors were taken into account,
    participants with type 2 diabetes were about twice as likely to need
    joint replacement surgery than those without type 2 diabetes.

    "High BMI, like age, is indeed independently associated with an
    increased risk of arthroplasty. Diabetes, however, is an independent
    risk factor as well," says Dr. Schett. "This finding means that
    diabetes, when present, increases the risk for arthroplasty, and thus
    also in a younger person and also in those with normal body
    weight."**

    Arthritis and diabetes experts alike welcome the study findings. "I
    don't know that [the study] is exactly a surprise, but they are one of
    the first to look at this in a systematic way over time," says Joanne
    Marie Jordan, MD, director of the Thurston Arthritis Research Center at
    the University of North Carolina at Chapel Hill.

    "One of the really nice parts about the study is that they looked at [an
    objective, measurable] outcome, which is joint replacement."

    "I think it is a very important study because it clearly establishes
    that severe osteoarthritis is a component of diabetes complications,"
    says George King, MD, research director of the Joslin Diabetes Center in
    Boston, and a professor of medicine at Harvard Medical School. "This has
    been talked about before – that arthritis and other musculoskeletal
    problems are increased in diabetics. But I think, as the authors point
    out, this is a population-based study that clearly establishes a link."

    The study authors say their research calls into question the commonly
    held view that osteoarthritis is a biomechanical – "wear and tear" –
    disorder and raises the proposition that it is also a metabolic one. How
    might diabetes raise the risk for developing osteoarthritis? The authors
    suggest it's possible high blood sugar levels promote the destruction of
    collagen (one of the main components of cartilage) or perhaps stimulate
    the production of inflammatory substances that ultimately damage the
    joint.

    Dr. Schett says the study suggests that osteoarthritis may be one
    manifestation of metabolic syndrome – a group of risk factors, such as
    obesity, high cholesterol and high blood pressure, that raise the
    chances of developing cardiovascular disease, stroke and type 2
    diabetes. "Effective management of the metabolic syndrome may help to
    prevent development of symptomatic joint disease," he adds.

    Dr. Jordan says this is a fertile area for study. "We've become
    increasingly aware of the fact that osteoarthritis and diabetes are
    conditions that may be part of one syndrome, or that at least travel
    together," she says. "It is critical for the public and health care
    providers to recognize this linkage and work together to break the
    cycle."

    ..
    ..
    Donna G.
    ..

    1) Rejoice always, Pray continually, Give thanks in all circumstances,
    For this is God's will for you in Christ Jesus. ( I Thessalonians
    5:16-18 NIV )

    2) It is not the mountain we conquer but ourselves.
    - Edmund Hillary

    3) ANGELS EXIST, but some times, since they don't all have wings, we
    call them FRIENDS......


  2. #2
    Harvey Guest

    Default Re: People with Type 2 Diabetes More Likely To Get Severe OA

    no opinion.....
    Harv


    "Donna G" wrote in message
    news:[email protected]..



    People With Type 2 Diabetes More Likely to Get Severe OA
    New research adds to notion that osteoarthritis is not just a "wear and
    tear" disease.
    By Jim Morelli

    11/6/12 Age and body mass index – the relationship of weight to height
    – are two well-recognized risk factors for the development of
    osteoarthritis, or OA. Now, a new study out of Europe adds type 2
    diabetes to the list. The study, published recently online in Diabetes
    Care, finds that type 2 diabetes doubles the risk of developing
    osteoarthritis that is severe enough to require joint replacement.

    "Data from this study show that age, body mass index and diabetes
    constitute three independent and strong risk factors for joint failure,"
    says study co-author Georg Schett, MD, chief of rheumatology and
    director of the department of internal medicine at the University of
    Erlangen-Nuremberg in Germany.

    Dr. Schett says one of the strengths of the study is that it was based
    on comprehensive and lengthy patient follow-up. The researchers analyzed
    the medical records of more than 900 diabetic and nondiabetic people
    over 20 years.

    The sample came from the Italian town of Bruneck, in which there is one
    single hospital and very little relocation of residents out of the area.

    The study participants, recruited in 1990 and followed until 2010, were
    examined every five years. The number of diabetic patients in the study
    was comparatively small: 69 patients in all. The nondiabetic patients
    numbered 858.

    The outcome the study focused on was joint replacement surgery. During
    the 20-year period, the researchers found 13 people in the diabetic
    group and 73 people in the nondiabetic group needed either a knee or hip
    replaced because of severe OA. The so-called "intervention rate" – the
    number of people who required total joint replacement, or arthroplasty

    – for the nondiabetic group was 5.3 percent. But for the diabetic
    group, it was 17.7 percent – more than three times greater. When age,
    body mass index and several other factors were taken into account,
    participants with type 2 diabetes were about twice as likely to need
    joint replacement surgery than those without type 2 diabetes.

    "High BMI, like age, is indeed independently associated with an
    increased risk of arthroplasty. Diabetes, however, is an independent
    risk factor as well," says Dr. Schett. "This finding means that
    diabetes, when present, increases the risk for arthroplasty, and thus
    also in a younger person and also in those with normal body
    weight."

    Arthritis and diabetes experts alike welcome the study findings. "I
    don't know that [the study] is exactly a surprise, but they are one of
    the first to look at this in a systematic way over time," says Joanne
    Marie Jordan, MD, director of the Thurston Arthritis Research Center at
    the University of North Carolina at Chapel Hill.

    "One of the really nice parts about the study is that they looked at [an
    objective, measurable] outcome, which is joint replacement."

    "I think it is a very important study because it clearly establishes
    that severe osteoarthritis is a component of diabetes complications,"
    says George King, MD, research director of the Joslin Diabetes Center in
    Boston, and a professor of medicine at Harvard Medical School. "This has
    been talked about before – that arthritis and other musculoskeletal
    problems are increased in diabetics. But I think, as the authors point
    out, this is a population-based study that clearly establishes a link."

    The study authors say their research calls into question the commonly
    held view that osteoarthritis is a biomechanical – "wear and tear" –
    disorder and raises the proposition that it is also a metabolic one. How
    might diabetes raise the risk for developing osteoarthritis? The authors
    suggest it's possible high blood sugar levels promote the destruction of
    collagen (one of the main components of cartilage) or perhaps stimulate
    the production of inflammatory substances that ultimately damage the
    joint.

    Dr. Schett says the study suggests that osteoarthritis may be one
    manifestation of metabolic syndrome – a group of risk factors, such as
    obesity, high cholesterol and high blood pressure, that raise the
    chances of developing cardiovascular disease, stroke and type 2
    diabetes. "Effective management of the metabolic syndrome may help to
    prevent development of symptomatic joint disease," he adds.

    Dr. Jordan says this is a fertile area for study. "We've become
    increasingly aware of the fact that osteoarthritis and diabetes are
    conditions that may be part of one syndrome, or that at least travel
    together," she says. "It is critical for the public and health care
    providers to recognize this linkage and work together to break the
    cycle."

    ..
    ..
    Donna G.
    ..

    1) Rejoice always, Pray continually, Give thanks in all circumstances,
    For this is God's will for you in Christ Jesus. ( I Thessalonians
    5:16-18 NIV )

    2) It is not the mountain we conquer but ourselves.
    - Edmund Hillary

    3) ANGELS EXIST, but some times, since they don't all have wings, we
    call them FRIENDS......


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